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Cheap flights from Mississippi to Panama City from $267

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Panama City departing on 2/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Mississippi to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:29 pm - 3:15 pm
GPT
-
PTY
21h 46m
2 stops
American Airlines Logo
4:05 pm - 10:13 am
PTY
-
GPT
19h 08m
2 stops
$481American Airlines
Thu, Feb 26 - Thu, Mar 5
United Airlines Logo
10:24 am - 7:38 pm
MOB
-
PTY
8h 14m
1 stop
United Airlines Logo
4:41 pm - 6:13 pm
PTY
-
MOB
26h 32m
1 stop
$484United Airlines
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
11:40 am - 6:38 pm
MEM
-
PTY
6h 58m
1 stop
United Airlines Logo
7:55 am - 9:40 pm
PTY
-
MEM
13h 45m
1 stop
$491United Airlines
Tue, Mar 24 - Tue, Mar 31
American Airlines Logo
5:55 pm - 2:20 pm
MEM
-
PTY
20h 25m
2 stops
American Airlines Logo
1:40 pm - 10:29 am
PTY
-
MEM
20h 49m
2 stops
$495American Airlines
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
12:00 pm - 7:38 pm
JAN
-
PTY
6h 38m
1 stop
United Airlines Logo
8:55 am - 9:59 pm
PTY
-
JAN
14h 04m
1 stop
$497United Airlines
Wed, Feb 25 - Sat, Feb 28
Copa Airlines Logo
6:15 am - 2:45 pm
MEM
-
PTY
7h 30m
1 stop
Copa Airlines Logo
4:41 pm - 9:08 am
PTY
-
MEM
17h 27m
1 stop
$550Copa Airlines
Wed, Feb 18 - Sat, Feb 21
Copa Airlines Logo
7:15 am - 6:37 pm
BTR
-
PTY
11h 22m
1 stop
Copa Airlines Logo
7:55 am - 5:33 pm
PTY
-
BTR
9h 38m
1 stop
$552Copa Airlines
Fri, Apr 10 - Mon, Apr 13
Multiple Airlines Logo
7:05 pm - 8:19 pm
MEM
-
PTY
24h 14m
1 stop
Multiple Airlines Logo
2:55 am - 6:11 pm
PTY
-
MEM
16h 16m
2 stops
$557Multiple Airlines
Sun, Feb 22 - Sat, Feb 28
Multiple Airlines Logo
6:18 am - 1:55 pm
BTR
-
PTY
6h 37m
1 stop
Multiple Airlines Logo
8:01 am - 5:32 pm
PTY
-
BTR
10h 31m
2 stops
$4,172Multiple Airlines
Mon, Feb 9 - Mon, Feb 16
WestJet Logo
12:43 pm - 9:20 am
MOB
-
PTY
19h 37m
2 stops
WestJet Logo
10:20 am - 10:58 pm
PTY
-
MOB
37h 38m
2 stops
$5,318WestJet
Wed, Feb 25 - Sat, Feb 28

Copa Airlines flights from Mississippi to Panama City

Our best Copa Airlines deals on Mississippi to Panama City flight tickets
Copa Airlines
Feb 18
MEM6:15 amMemphis
7h 30m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Feb 21
PTY4:41 pmPanama City Tocumen Intl
17h 27m
1 stop
MEM9:08 amMemphis
$550
Copa Airlines
Apr 10
BTR7:15 amBaton Rouge Ryan
11h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 13
PTY7:55 amPanama City Tocumen Intl
9h 38m
1 stop
BTR5:33 pmBaton Rouge Ryan
$552
Copa Airlines
Feb 5
GPT1:57 pmGulfport Biloxi Regional
23h 48m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Feb 12
PTY4:41 pmPanama City Tocumen Intl
27h 53m
1 stop
GPT7:34 pmGulfport Biloxi Regional
$567

American Airlines flights from Mississippi to Panama City

Our best American Airlines deals on Mississippi to Panama City flight tickets
American Airlines
Feb 26
GPT4:29 pmGulfport Biloxi Regional
21h 46m
2 stops
PTY3:15 pmPanama City Tocumen Intl
Mar 5
PTY4:05 pmPanama City Tocumen Intl
19h 08m
2 stops
GPT10:13 amGulfport Biloxi Regional
$481
American Airlines
Mar 24
MEM5:55 pmMemphis
20h 25m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 31
PTY1:40 pmPanama City Tocumen Intl
20h 49m
2 stops
MEM10:29 amMemphis
$495
American Airlines
Feb 25
MEM4:23 pmMemphis
20h 17m
2 stops
PTY1:40 pmPanama City Tocumen Intl
Mar 4
PTY2:40 pmPanama City Tocumen Intl
10h 15m
1 stop
MEM11:55 pmMemphis
$515

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 2/26

4:29 pm-3:15 pm

2 stops21h 46m

Panama City Tocumen Intl

Thu 3/5

4:05 pm-10:13 am

2 stops19h 08m

$481

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Wed 2/25

10:24 am-7:38 pm

1 stop8h 14m

Panama City Tocumen Intl

Sat 2/28

4:41 pm-6:13 pm

1 stop26h 32m

$484

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 3/24

11:40 am-6:38 pm

1 stop6h 58m

Panama City Tocumen Intl

Tue 3/31

7:55 am-9:40 pm

1 stop13h 45m

$491

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 3/24

5:55 pm-2:20 pm

2 stops20h 25m

Panama City Tocumen Intl

Tue 3/31

1:40 pm-10:29 am

2 stops20h 49m

$495

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Wed 2/25

12:00 pm-7:38 pm

1 stop6h 38m

Panama City Tocumen Intl

Sat 2/28

8:55 am-9:59 pm

1 stop14h 04m

$497

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 2/18

6:15 am-2:45 pm

1 stop7h 30m

Panama City Tocumen Intl

Sat 2/21

4:41 pm-9:08 am

1 stop17h 27m

$550

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Fri 4/10

7:15 am-6:37 pm

1 stop11h 22m

Panama City Tocumen Intl

Mon 4/13

7:55 am-5:33 pm

1 stop9h 38m

$552

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sun 2/22

7:05 pm-8:19 pm

1 stop24h 14m

Panama City Tocumen Intl

Sat 2/28

2:55 am-6:11 pm

2 stops16h 16m

$557

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Mon 2/9

6:18 am-1:55 pm

1 stop6h 37m

Panama City Tocumen Intl

Mon 2/16

8:01 am-5:32 pm

2 stops10h 31m

$4,172

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Wed 2/25

12:43 pm-9:20 am

2 stops19h 37m

Panama City Tocumen Intl

Sat 2/28

10:20 am-10:58 pm

2 stops37h 38m

$5,318

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Mississippi to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Mississippi to Panama City Tocumen Intl?

United Airlines and American Airlines are the most popular carriers operating from Mississippi to Panama City Tocumen Intl

Cheap Mississippi to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama City

Fastest flight time

6h 30m

Direct flights

None
The fastest flight from Mississippi to Panama City takes 6h 30m
There are no direct flights from Mississippi to Panama City. There are no popular flight routes from Mississippi to Panama City.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Panama City Tocumen Intl Airport?

    Prices for flights from Mississippi to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Mississippi to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Mississippi to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama City

Compare and see reviews for airlines that fly from Mississippi to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $445Free CancellationRating
7.4
9,143 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Panama City?

Finding the right flight to Panama City from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Mississippi to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Mississippi. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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