Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Mississippi to Panama City from $306

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Panama City departing on 5/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Mississippi to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:50 am - 2:14 pm
MEM
-
PTY
7h 24m
1 stop
United Airlines Logo
10:00 am - 7:50 pm
PTY
-
MEM
9h 50m
1 stop
$467United Airlines
Mon, Aug 24 - Thu, Aug 27
United Airlines Logo
11:44 am - 6:37 pm
MEM
-
PTY
6h 53m
1 stop
United Airlines Logo
3:30 pm - 2:43 pm
PTY
-
MEM
23h 13m
2 stops
$471United Airlines
Mon, Aug 24 - Thu, Aug 27
United Airlines Logo
7:00 am - 4:12 pm
MEM
-
PTY
9h 12m
1 stop
United Airlines Logo
10:55 pm - 3:26 pm
PTY
-
MEM
16h 31m
1 stop
$501United Airlines
Mon, Jul 20 - Fri, Jul 31
United Airlines Logo
6:50 am - 6:37 pm
MEM
-
PTY
11h 47m
1 stop
United Airlines Logo
3:30 pm - 2:43 pm
PTY
-
MEM
23h 13m
2 stops
$503United Airlines
Mon, Aug 24 - Thu, Aug 27
United Airlines Logo
6:40 pm - 2:14 pm
MEM
-
PTY
19h 34m
2 stops
United Airlines Logo
3:30 pm - 11:05 am
PTY
-
MEM
19h 35m
2 stops
$505United Airlines
Sat, Aug 1 - Thu, Aug 6
United Airlines Logo
6:00 am - 7:31 pm
MEM
-
PTY
13h 31m
1 stop
United Airlines Logo
3:30 pm - 6:09 pm
PTY
-
MEM
26h 39m
1 stop
$507United Airlines
Mon, Aug 24 - Thu, Aug 27
American Airlines Logo
4:24 pm - 12:14 pm
JAN
-
PTY
19h 50m
2 stops
American Airlines Logo
1:14 pm - 11:53 am
PTY
-
JAN
22h 39m
2 stops
$561American Airlines
Wed, Jul 22 - Mon, Jul 27
American Airlines Logo
11:48 am - 12:14 pm
MOB
-
PTY
24h 26m
2 stops
American Airlines Logo
1:14 pm - 12:17 pm
PTY
-
MOB
23h 03m
2 stops
$661American Airlines
Mon, Jul 13 - Mon, Jul 20
American Airlines Logo
9:52 am - 12:46 pm
JAN
-
PTY
26h 54m
2 stops
American Airlines Logo
1:49 pm - 11:29 pm
PTY
-
JAN
9h 40m
1 stop
$671American Airlines
Sat, May 9 - Sat, May 16
Delta Logo
6:30 am - 1:05 pm
GPT
-
PTY
6h 35m
1 stop
Delta Logo
2:24 pm - 10:14 pm
PTY
-
GPT
7h 50m
1 stop
$1,153Delta
Mon, Jul 13 - Mon, Jul 20

Delta flights from Mississippi to Panama City

Our best Delta deals on Mississippi to Panama City flight tickets
Delta
Jun 3
MEM6:30 amMemphis
6h 20m
1 stop
PTY12:50 pmPanama City Tocumen Intl
Jun 10
PTY2:24 pmPanama City Tocumen Intl
9h 02m
1 stop
MEM11:26 pmMemphis
$547
Delta
Jun 3
MEM5:30 amMemphis
7h 20m
1 stop
PTY12:50 pmPanama City Tocumen Intl
Jun 10
PTY2:24 pmPanama City Tocumen Intl
9h 02m
1 stop
MEM11:26 pmMemphis
$566
Delta
Jul 21
MEM5:15 amMemphis
7h 50m
1 stop
PTY1:05 pmPanama City Tocumen Intl
Aug 1
PTY2:27 pmPanama City Tocumen Intl
17h 24m
1 stop
MEM7:51 amMemphis
$681

American Airlines flights from Mississippi to Panama City

Our best American Airlines deals on Mississippi to Panama City flight tickets
American Airlines
Jul 22
JAN4:24 pmJackson-Evers Intl
19h 50m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Jul 27
PTY1:14 pmPanama City Tocumen Intl
22h 39m
2 stops
JAN11:53 amJackson-Evers Intl
$561
American Airlines
May 11
MEM6:07 pmMemphis
18h 39m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Jun 1
PTY1:14 pmPanama City Tocumen Intl
20h 48m
2 stops
MEM10:02 amMemphis
$585
American Airlines
May 14
MEM6:07 pmMemphis
18h 39m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 20
PTY1:49 pmPanama City Tocumen Intl
20h 18m
2 stops
MEM10:07 amMemphis
$610

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 8/24

6:50 am-2:14 pm

1 stop7h 24m

Panama City Tocumen Intl

Thu 8/27

10:00 am-7:50 pm

1 stop9h 50m

$467

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 8/24

11:44 am-6:37 pm

1 stop6h 53m

Panama City Tocumen Intl

Thu 8/27

3:30 pm-2:43 pm

2 stops23h 13m

$471

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 7/20

7:00 am-4:12 pm

1 stop9h 12m

Panama City Tocumen Intl

Fri 7/31

10:55 pm-3:26 pm

1 stop16h 31m

$501

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 8/24

6:50 am-6:37 pm

1 stop11h 47m

Panama City Tocumen Intl

Thu 8/27

3:30 pm-2:43 pm

2 stops23h 13m

$503

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 8/1

6:40 pm-2:14 pm

2 stops19h 34m

Panama City Tocumen Intl

Thu 8/6

3:30 pm-11:05 am

2 stops19h 35m

$505

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 8/24

6:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Thu 8/27

3:30 pm-6:09 pm

1 stop26h 39m

$507

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Wed 7/22

4:24 pm-12:14 pm

2 stops19h 50m

Panama City Tocumen Intl

Mon 7/27

1:14 pm-11:53 am

2 stops22h 39m

$561

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Mon 7/13

11:48 am-12:14 pm

2 stops24h 26m

Panama City Tocumen Intl

Mon 7/20

1:14 pm-12:17 pm

2 stops23h 03m

$661

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Sat 5/9

9:52 am-12:46 pm

2 stops26h 54m

Panama City Tocumen Intl

Sat 5/16

1:49 pm-11:29 pm

1 stop9h 40m

$671
Quickest round-trip

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 7/13

6:30 am-1:05 pm

1 stop6h 35m

Panama City Tocumen Intl

Mon 7/20

2:24 pm-10:14 pm

1 stop7h 50m

$1,153

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

See travel insights to Panama City from

How to get the cheapest flight ticket from Mississippi to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from Mississippi to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you’re not able to fly to Panama City in October, then June is your next best option. Flight prices from Mississippi to Panama City during June average around $505.

Cheap Mississippi to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama City

Fastest flight time

6h 31m

Direct flights

None
The fastest flight from Mississippi to Panama City takes 6h 31m
There are no direct flights from Mississippi to Panama City. There are no popular flight routes from Mississippi to Panama City.
Search flight deals

Frequently asked questions about flying from Mississippi to Panama City

  • When did momondo last update prices for flights from Mississippi to Panama City Tocumen Intl Airport?

    Prices for flights from Mississippi to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Mississippi to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Mississippi to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama City

Compare and see reviews for airlines that fly from Mississippi to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $445Free CancellationRating
7.4
9,665 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Panama City?

Finding the right flight to Panama City from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Mississippi to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Mississippi. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 5/27
Wed 6/3
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama