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Cheap flights from Mississippi to Panama City from $205

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Panama City departing on 1/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Mississippi to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:29 pm - 1:27 pmGPT-PTY
18h 58m2 stops
American Airlines Logo
2:27 pm - 12:31 pmPTY-GPT
23h 04m2 stops
$440American Airlines
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Tue, Jan 20 - Tue, Feb 3
United Airlines Logo
4:55 pm - 2:45 pmGPT-PTY
20h 50m1 stop
United Airlines Logo
8:55 am - 4:01 pmPTY-GPT
8h 06m1 stop
$443United Airlines
Find Deal
Sun, Feb 15 - Thu, Feb 19
United Airlines Logo
7:00 am - 2:45 pmJAN-PTY
6h 45m1 stop
United Airlines Logo
4:41 pm - 4:01 pmPTY-JAN
24h 20m1 stop
$443United Airlines
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Mon, Feb 23 - Tue, Feb 24
American Airlines Logo
3:20 pm - 1:27 pmMOB-PTY
21h 07m2 stops
American Airlines Logo
4:50 pm - 10:49 amPTY-MOB
18h 59m2 stops
$460American Airlines
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Thu, Jan 8 - Thu, Jan 15
American Airlines Logo
5:29 pm - 1:27 pmGPT-PTY
18h 58m2 stops
American Airlines Logo
5:00 pm - 12:31 pmPTY-GPT
20h 31m2 stops
$460American Airlines
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Tue, Jan 20 - Sat, Jan 31
American Airlines Logo
3:39 pm - 1:27 pmJAN-PTY
20h 48m2 stops
American Airlines Logo
4:50 pm - 12:15 pmPTY-JAN
20h 25m2 stops
$460American Airlines
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Thu, Jan 8 - Thu, Jan 15
United Airlines Logo
7:00 am - 7:38 pmGPT-PTY
11h 38m1 stop
United Airlines Logo
4:41 pm - 1:22 pmPTY-GPT
21h 41m1 stop
$463United Airlines
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Mon, Jan 19 - Sat, Jan 31
Delta Logo
6:00 am - 1:55 pmMEM-PTY
6h 55m1 stop
Delta Logo
3:20 pm - 11:17 pmPTY-MEM
8h 57m1 stop
$490Delta
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Tue, Feb 10 - Thu, Feb 12
Delta Logo
5:50 pm - 1:55 pmBTR-PTY
19h 05m1 stop
Delta Logo
3:20 pm - 10:01 pmPTY-BTR
7h 41m1 stop
$540Delta
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Sun, Feb 8 - Thu, Feb 12
Delta Logo
5:48 am - 7:59 pmJAN-PTY
13h 11m1 stop
Delta Logo
8:05 am - 7:30 pmPTY-JAN
12h 25m1 stop
$586Delta
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Sat, Dec 6 - Sat, Dec 13

American Airlines flights from Mississippi to Panama City

Our best American Airlines deals on Mississippi to Panama City flight tickets
American Airlines
Jan 20
GPT5:29 pmGulfport Biloxi Regional
18h 58m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 3
PTY2:27 pmPanama City Tocumen Intl
23h 04m
2 stops
GPT12:31 pmGulfport Biloxi Regional
$440
Find similar
American Airlines
Jan 20
GPT5:29 pmGulfport Biloxi Regional
18h 58m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 31
PTY5:00 pmPanama City Tocumen Intl
20h 31m
2 stops
GPT12:31 pmGulfport Biloxi Regional
$460
Find similar
American Airlines
Jan 20
GPT6:33 pmGulfport Biloxi Regional
17h 54m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 1
PTY4:50 pmPanama City Tocumen Intl
26h 13m
2 stops
GPT6:03 pmGulfport Biloxi Regional
$465
Find similar

United Airlines flights from Mississippi to Panama City

Our best United Airlines deals on Mississippi to Panama City flight tickets
United Airlines
Feb 15
GPT4:55 pmGulfport Biloxi Regional
20h 50m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Feb 19
PTY8:55 amPanama City Tocumen Intl
8h 06m
1 stop
GPT4:01 pmGulfport Biloxi Regional
$443
Find similar
United Airlines
Jan 19
GPT7:00 amGulfport Biloxi Regional
11h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 31
PTY4:41 pmPanama City Tocumen Intl
21h 41m
1 stop
GPT1:22 pmGulfport Biloxi Regional
$463
Find similar
United Airlines
Jan 20
GPT4:42 pmGulfport Biloxi Regional
21h 03m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Feb 1
PTY4:41 pmPanama City Tocumen Intl
21h 41m
1 stop
GPT1:22 pmGulfport Biloxi Regional
$470
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 1/20

5:29 pm-1:27 pm

2 stops18h 58m

Panama City Tocumen Intl

Tue 2/3

2:27 pm-12:31 pm

2 stops23h 04m

$440

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 2/15

4:55 pm-2:45 pm

1 stop20h 50m

Panama City Tocumen Intl

Thu 2/19

8:55 am-4:01 pm

1 stop8h 06m

$443

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Mon 2/23

7:00 am-2:45 pm

1 stop6h 45m

Panama City Tocumen Intl

Tue 2/24

4:41 pm-4:01 pm

1 stop24h 20m

$443

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Thu 1/8

3:20 pm-1:27 pm

2 stops21h 07m

Panama City Tocumen Intl

Thu 1/15

4:50 pm-10:49 am

2 stops18h 59m

$460

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 1/20

5:29 pm-1:27 pm

2 stops18h 58m

Panama City Tocumen Intl

Sat 1/31

5:00 pm-12:31 pm

2 stops20h 31m

$460

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Thu 1/8

3:39 pm-1:27 pm

2 stops20h 48m

Panama City Tocumen Intl

Thu 1/15

4:50 pm-12:15 pm

2 stops20h 25m

$460

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 1/19

7:00 am-7:38 pm

1 stop11h 38m

Panama City Tocumen Intl

Sat 1/31

4:41 pm-1:22 pm

1 stop21h 41m

$463

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 2/10

6:00 am-1:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Thu 2/12

3:20 pm-11:17 pm

1 stop8h 57m

$490

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Sun 2/8

5:50 pm-1:55 pm

1 stop19h 05m

Panama City Tocumen Intl

Thu 2/12

3:20 pm-10:01 pm

1 stop7h 41m

$540

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Sat 12/6

5:48 am-7:59 pm

1 stop13h 11m

Panama City Tocumen Intl

Sat 12/13

8:05 am-7:30 pm

1 stop12h 25m

$586

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Mississippi to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Saturday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $417. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $1,055. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Cheap Mississippi to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama City

Fastest flight time

6h 38m

Direct flights

None
The fastest flight from Mississippi to Panama City takes 6h 38m
There are no direct flights from Mississippi to Panama City. There are no popular flight routes from Mississippi to Panama City.
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  • When did momondo last update prices for flights from Mississippi to Panama City Tocumen Intl Airport?

    Prices for flights from Mississippi to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Mississippi to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Mississippi to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama City

Compare and see reviews for airlines that fly from Mississippi to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $445Free CancellationRating
7.4
9,046 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Panama City?

Finding the right flight to Panama City from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Mississippi to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Mississippi. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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