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Cheap flights from Mississippi to Panama City from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Panama City departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Mississippi to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:53 pm - 4:12 pm
MEM
-
PTY
21h 19m
1 stop
United Airlines Logo
7:55 am - 7:54 pm
PTY
-
MEM
11h 59m
1 stop
$434United Airlines
Sun, Jun 7 - Thu, Jun 11
United Airlines Logo
6:15 am - 4:12 pm
MEM
-
PTY
9h 57m
1 stop
United Airlines Logo
3:30 pm - 9:07 am
PTY
-
MEM
17h 37m
1 stop
$451United Airlines
Sat, Apr 25 - Wed, Apr 29
American Airlines Logo
7:01 pm - 12:46 pm
MEM
-
PTY
17h 45m
2 stops
American Airlines Logo
1:14 pm - 10:03 am
PTY
-
MEM
20h 49m
2 stops
$455American Airlines
Fri, May 15 - Wed, May 27
American Airlines Logo
7:01 pm - 12:46 pm
MEM
-
PTY
17h 45m
2 stops
American Airlines Logo
1:49 pm - 11:42 pm
PTY
-
MEM
9h 53m
1 stop
$461American Airlines
Mon, May 11 - Fri, May 15
United Airlines Logo
6:15 am - 6:37 pm
MEM
-
PTY
12h 22m
1 stop
United Airlines Logo
3:30 pm - 9:00 am
PTY
-
MEM
17h 30m
1 stop
$467United Airlines
Mon, Apr 13 - Mon, Apr 20
United Airlines Logo
4:09 pm - 4:04 am
MEM
-
PTY
11h 55m
1 stop
United Airlines Logo
3:30 pm - 9:00 am
PTY
-
MEM
17h 30m
1 stop
$471United Airlines
Fri, Apr 24 - Mon, Apr 27
United Airlines Logo
11:35 am - 6:37 pm
MEM
-
PTY
7h 02m
1 stop
United Airlines Logo
7:55 am - 9:43 pm
PTY
-
MEM
13h 48m
1 stop
$475United Airlines
Fri, May 15 - Sun, May 17
Copa Airlines Logo
4:57 pm - 6:37 pm
JAN
-
PTY
25h 40m
1 stop
Copa Airlines Logo
3:30 pm - 11:11 am
PTY
-
JAN
19h 41m
1 stop
$544Copa Airlines
Wed, Apr 1 - Wed, Apr 8
Copa Airlines Logo
4:55 pm - 1:45 pm
JAN
-
PTY
20h 50m
1 stop
Copa Airlines Logo
3:41 pm - 11:13 am
PTY
-
JAN
19h 32m
1 stop
$605Copa Airlines
Sun, Mar 22 - Fri, Mar 27
WestJet Logo
5:55 pm - 8:20 am
GPT
-
PTY
38h 25m
2 stops
WestJet Logo
9:20 am - 10:13 pm
PTY
-
GPT
36h 53m
2 stops
$1,191WestJet
Tue, Apr 14 - Tue, Apr 21

Copa Airlines flights from Mississippi to Panama City

Our best Copa Airlines deals on Mississippi to Panama City flight tickets
Copa Airlines
Apr 1
JAN4:57 pmJackson-Evers Intl
25h 40m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 8
PTY3:30 pmPanama City Tocumen Intl
19h 41m
1 stop
JAN11:11 amJackson-Evers Intl
$544
Copa Airlines
Mar 22
JAN4:55 pmJackson-Evers Intl
20h 50m
1 stop
PTY1:45 pmPanama City Tocumen Intl
Mar 27
PTY3:41 pmPanama City Tocumen Intl
19h 32m
1 stop
JAN11:13 amJackson-Evers Intl
$605
Copa Airlines
Mar 8
MEM11:40 amMemphis
28h 27m
1 stop
PTY4:07 pmPanama City Tocumen Intl
Mar 12
PTY3:41 pmPanama City Tocumen Intl
7h 39m
1 stop
MEM11:20 pmMemphis
$713

American Airlines flights from Mississippi to Panama City

Our best American Airlines deals on Mississippi to Panama City flight tickets
American Airlines
May 15
MEM7:01 pmMemphis
17h 45m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 27
PTY1:14 pmPanama City Tocumen Intl
20h 49m
2 stops
MEM10:03 amMemphis
$455
American Airlines
May 11
MEM7:01 pmMemphis
17h 45m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 15
PTY1:49 pmPanama City Tocumen Intl
9h 53m
1 stop
MEM11:42 pmMemphis
$461
American Airlines
May 1
MEM7:01 pmMemphis
17h 45m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 4
PTY1:49 pmPanama City Tocumen Intl
22h 39m
2 stops
MEM12:28 pmMemphis
$479

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sun 6/7

6:53 pm-4:12 pm

1 stop21h 19m

Panama City Tocumen Intl

Thu 6/11

7:55 am-7:54 pm

1 stop11h 59m

$434

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 4/25

6:15 am-4:12 pm

1 stop9h 57m

Panama City Tocumen Intl

Wed 4/29

3:30 pm-9:07 am

1 stop17h 37m

$451

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Fri 5/15

7:01 pm-12:46 pm

2 stops17h 45m

Panama City Tocumen Intl

Wed 5/27

1:14 pm-10:03 am

2 stops20h 49m

$455

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 5/11

7:01 pm-12:46 pm

2 stops17h 45m

Panama City Tocumen Intl

Fri 5/15

1:49 pm-11:42 pm

1 stop9h 53m

$461

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 4/13

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Mon 4/20

3:30 pm-9:00 am

1 stop17h 30m

$467

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Fri 4/24

4:09 pm-4:04 am

1 stop11h 55m

Panama City Tocumen Intl

Mon 4/27

3:30 pm-9:00 am

1 stop17h 30m

$471

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Fri 5/15

11:35 am-6:37 pm

1 stop7h 02m

Panama City Tocumen Intl

Sun 5/17

7:55 am-9:43 pm

1 stop13h 48m

$475

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Wed 4/1

4:57 pm-6:37 pm

1 stop25h 40m

Panama City Tocumen Intl

Wed 4/8

3:30 pm-11:11 am

1 stop19h 41m

$544

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Sun 3/22

4:55 pm-1:45 pm

1 stop20h 50m

Panama City Tocumen Intl

Fri 3/27

3:41 pm-11:13 am

1 stop19h 32m

$605

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 4/14

5:55 pm-8:20 am

2 stops38h 25m

Panama City Tocumen Intl

Tue 4/21

9:20 am-10:13 pm

2 stops36h 53m

$1,191

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Mississippi to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Mississippi to Panama City Tocumen Intl?

United Airlines, Copa Airlines, and American Airlines are the most popular carriers operating from Mississippi to Panama City Tocumen Intl

Cheap Mississippi to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama City

Fastest flight time

6h 37m

Direct flights

None
The fastest flight from Mississippi to Panama City takes 6h 37m
There are no direct flights from Mississippi to Panama City. There are no popular flight routes from Mississippi to Panama City.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Panama City Tocumen Intl Airport?

    Prices for flights from Mississippi to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Mississippi to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Mississippi to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama City

Compare and see reviews for airlines that fly from Mississippi to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $445Free CancellationRating
7.4
9,382 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Panama City?

Finding the right flight to Panama City from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Mississippi to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Mississippi. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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