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Cheap flights from Buffalo to Panama City from $193

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama City departing on 3/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Buffalo to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:39 pm - 10:30 am
BUF
-
PTY
15h 51m
2 stops
Multiple Airlines Logo
3:50 pm - 9:00 am
PTY
-
BUF
16h 10m
2 stops
$500Multiple Airlines
Sat, May 9 - Fri, May 15
Multiple Airlines Logo
7:58 pm - 6:55 pm
BUF
-
PTY
23h 57m
2 stops
Multiple Airlines Logo
3:50 pm - 9:02 am
PTY
-
BUF
16h 12m
2 stops
$535Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
7:02 pm - 10:30 am
BUF
-
PTY
16h 28m
2 stops
Multiple Airlines Logo
3:50 pm - 8:58 am
PTY
-
BUF
16h 08m
2 stops
$538Multiple Airlines
Wed, Apr 15 - Thu, Apr 23
United Airlines Logo
10:31 am - 7:31 pm
BUF
-
PTY
10h 00m
1 stop
United Airlines Logo
10:55 pm - 9:50 am
PTY
-
BUF
9h 55m
1 stop
$539United Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
7:58 pm - 6:55 pm
BUF
-
PTY
23h 57m
2 stops
Multiple Airlines Logo
11:25 am - 9:02 am
PTY
-
BUF
20h 37m
3 stops
$541Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
United Airlines Logo
11:29 am - 8:02 pm
BUF
-
PTY
8h 33m
1 stop
United Airlines Logo
4:41 pm - 8:51 pm
PTY
-
BUF
28h 10m
2 stops
$543United Airlines
Tue, Feb 17 - Mon, Feb 23
Multiple Airlines Logo
7:02 pm - 2:55 pm
BUF
-
PTY
20h 53m
3 stops
Multiple Airlines Logo
3:50 pm - 8:58 am
PTY
-
BUF
16h 08m
2 stops
$544Multiple Airlines
Wed, Apr 15 - Thu, Apr 23
Multiple Airlines Logo
7:58 pm - 2:55 pm
BUF
-
PTY
19h 57m
3 stops
Multiple Airlines Logo
11:25 am - 9:02 am
PTY
-
BUF
20h 37m
3 stops
$548Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
6:00 am - 10:30 am
BUF
-
PTY
28h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 9:40 am
PTY
-
BUF
17h 50m
2 stops
$551Multiple Airlines
Thu, Feb 26 - Sun, Mar 1
Multiple Airlines Logo
7:58 pm - 6:55 pm
BUF
-
PTY
23h 57m
2 stops
Multiple Airlines Logo
3:50 pm - 9:04 am
PTY
-
BUF
16h 14m
2 stops
$555Multiple Airlines
Fri, Mar 20 - Fri, Mar 27

American Airlines flights from Buffalo to Panama City

Our best American Airlines deals on Buffalo to Panama City flight tickets
American Airlines
Apr 1
BUF5:59 pmBuffalo
22h 02m
2 stops
PTY3:01 pmPanama City Tocumen Intl
Apr 9
PTY1:49 pmPanama City Tocumen Intl
23h 32m
2 stops
BUF2:21 pmBuffalo
$570
American Airlines
Jul 23
BUF4:47 pmBuffalo
20h 23m
2 stops
PTY12:10 pmPanama City Tocumen Intl
Jul 26
PTY1:10 pmPanama City Tocumen Intl
19h 26m
2 stops
BUF9:36 amBuffalo
$611
American Airlines
Mar 14
BUF7:02 pmBuffalo
20h 18m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 21
PTY3:10 pmPanama City Tocumen Intl
20h 04m
2 stops
BUF12:14 pmBuffalo
$653

Azul flights from Buffalo to Panama City

Our best Azul deals on Buffalo to Panama City flight tickets
Azul
Jul 22
BUF6:00 amBuffalo
23h 04m
1 stop
PTY4:04 amPanama City Tocumen Intl
Jul 26
PTY10:55 pmPanama City Tocumen Intl
18h 27m
1 stop
BUF6:22 pmBuffalo
$903
Azul
Feb 26
BUF6:00 amBuffalo
14h 02m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Mar 1
PTY10:00 amPanama City Tocumen Intl
28h 13m
2 stops
BUF2:13 pmBuffalo
$990

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 5/9

7:39 pm-10:30 am

2 stops15h 51m

Panama City Tocumen Intl

Fri 5/15

3:50 pm-9:00 am

2 stops16h 10m

$500

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 3/18

7:58 pm-6:55 pm

2 stops23h 57m

Panama City Tocumen Intl

Wed 3/25

3:50 pm-9:02 am

2 stops16h 12m

$535

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 4/15

7:02 pm-10:30 am

2 stops16h 28m

Panama City Tocumen Intl

Thu 4/23

3:50 pm-8:58 am

2 stops16h 08m

$538

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 4/30

10:31 am-7:31 pm

1 stop10h 00m

Panama City Tocumen Intl

Sun 5/3

10:55 pm-9:50 am

1 stop9h 55m

$539

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 3/18

7:58 pm-6:55 pm

2 stops23h 57m

Panama City Tocumen Intl

Wed 3/25

11:25 am-9:02 am

3 stops20h 37m

$541

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 2/17

11:29 am-8:02 pm

1 stop8h 33m

Panama City Tocumen Intl

Mon 2/23

4:41 pm-8:51 pm

2 stops28h 10m

$543

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 4/15

7:02 pm-2:55 pm

3 stops20h 53m

Panama City Tocumen Intl

Thu 4/23

3:50 pm-8:58 am

2 stops16h 08m

$544

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 3/18

7:58 pm-2:55 pm

3 stops19h 57m

Panama City Tocumen Intl

Wed 3/25

11:25 am-9:02 am

3 stops20h 37m

$548

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 2/26

6:00 am-10:30 am

2 stops28h 30m

Panama City Tocumen Intl

Sun 3/1

3:50 pm-9:40 am

2 stops17h 50m

$551

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 3/20

7:58 pm-6:55 pm

2 stops23h 57m

Panama City Tocumen Intl

Fri 3/27

3:50 pm-9:04 am

2 stops16h 14m

$555

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Buffalo to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and Panama City?

When to book flights from Buffalo to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Panama City (BUF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama City

Fastest flight time

11h 08m

Direct flights

None
The fastest flight from Buffalo to Panama City takes 11h 08m
There are no direct flights from Buffalo to Panama City. There are no popular flight routes from Buffalo to Panama City.
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  • How far is Buffalo to Panama City Tocumen Intl by plane?

    Buffalo and Panama City Tocumen Intl are 2341.1 mi apart from one another. Flights usually cover this in 11h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Buffalo Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Panama City?

Best airlines flying from Buffalo to Panama City

Compare and see reviews for airlines that fly from Buffalo to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $497Free CancellationRating
7.9
8,159 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama City?

Finding the right flight to Panama City from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Buffalo to Panama City with flexible booking policies on momondo?

Flights from Buffalo to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Buffalo.

I’m not ready to book a flight from Buffalo to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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