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Cheap flights from Buffalo to Panama City from $261

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama City departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Buffalo to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:41 pm - 8:34 pm
BUF
-
PTY
8h 53m
1 stop
Multiple Airlines Logo
10:26 am - 10:41 am
PTY
-
BUF
23h 15m
1 stop
$570Multiple Airlines
Sat, May 9 - Sat, May 16
Multiple Airlines Logo
7:02 pm - 10:30 am
BUF
-
PTY
16h 28m
2 stops
Multiple Airlines Logo
11:25 am - 8:58 am
PTY
-
BUF
20h 33m
3 stops
$576Multiple Airlines
Tue, Apr 14 - Wed, Apr 22
Multiple Airlines Logo
7:55 pm - 10:30 am
BUF
-
PTY
15h 35m
2 stops
Multiple Airlines Logo
3:50 pm - 9:27 pm
PTY
-
BUF
28h 37m
2 stops
$577Multiple Airlines
Fri, May 8 - Fri, May 15
Multiple Airlines Logo
7:02 pm - 10:30 am
BUF
-
PTY
16h 28m
2 stops
Multiple Airlines Logo
5:30 am - 8:58 am
PTY
-
BUF
26h 28m
2 stops
$580Multiple Airlines
Tue, Apr 14 - Wed, Apr 22
Multiple Airlines Logo
7:55 pm - 2:55 pm
BUF
-
PTY
20h 00m
3 stops
Multiple Airlines Logo
3:50 pm - 9:27 pm
PTY
-
BUF
28h 37m
2 stops
$583Multiple Airlines
Fri, May 8 - Fri, May 15
Multiple Airlines Logo
7:02 pm - 2:55 pm
BUF
-
PTY
20h 53m
3 stops
Multiple Airlines Logo
5:30 am - 8:58 am
PTY
-
BUF
26h 28m
2 stops
$586Multiple Airlines
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
7:55 pm - 10:30 am
BUF
-
PTY
15h 35m
2 stops
Multiple Airlines Logo
3:50 pm - 9:31 am
PTY
-
BUF
16h 41m
2 stops
$588Multiple Airlines
Sat, May 9 - Sat, May 16
Multiple Airlines Logo
7:00 am - 10:30 am
BUF
-
PTY
28h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 2:58 pm
PTY
-
BUF
22h 08m
2 stops
$618Multiple Airlines
Sun, Apr 26 - Sat, May 2
Multiple Airlines Logo
7:02 pm - 2:55 pm
BUF
-
PTY
20h 53m
3 stops
Multiple Airlines Logo
11:25 am - 8:58 am
PTY
-
BUF
20h 33m
3 stops
$621Multiple Airlines
Wed, Apr 15 - Wed, Apr 22
United Airlines Logo
6:55 pm - 4:04 am
BUF
-
PTY
10h 09m
1 stop
United Airlines Logo
10:55 pm - 9:47 am
PTY
-
BUF
9h 52m
1 stop
$629United Airlines
Tue, Apr 14 - Wed, Apr 22

United Airlines flights from Buffalo to Panama City

Our best United Airlines deals on Buffalo to Panama City flight tickets
United Airlines
Apr 14
BUF6:55 pmBuffalo
10h 09m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 22
PTY10:55 pmPanama City Tocumen Intl
9h 52m
1 stop
BUF9:47 amBuffalo
$629
United Airlines
Apr 14
BUF7:00 amBuffalo
12h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Apr 22
PTY10:55 pmPanama City Tocumen Intl
9h 52m
1 stop
BUF9:47 amBuffalo
$633
United Airlines
Sep 22
BUF5:52 pmBuffalo
21h 22m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Sep 25
PTY3:20 pmPanama City Tocumen Intl
17h 29m
2 stops
BUF9:49 amBuffalo
$640

Delta flights from Buffalo to Panama City

Our best Delta deals on Buffalo to Panama City flight tickets
Delta
Apr 27
BUF5:30 pmBuffalo
20h 32m
2 stops
PTY1:02 pmPanama City Tocumen Intl
May 2
PTY2:27 pmPanama City Tocumen Intl
8h 10m
1 stop
BUF11:37 pmBuffalo
$653
Delta
Mar 30
BUF5:50 pmBuffalo
20h 13m
2 stops
PTY1:03 pmPanama City Tocumen Intl
Apr 4
PTY2:28 pmPanama City Tocumen Intl
18h 14m
2 stops
BUF9:42 amBuffalo
$1,001
Delta
Apr 14
BUF6:00 amBuffalo
8h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 22
PTY2:27 pmPanama City Tocumen Intl
8h 10m
1 stop
BUF11:37 pmBuffalo
$2,676

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 5/9

12:41 pm-8:34 pm

1 stop8h 53m

Panama City Tocumen Intl

Sat 5/16

10:26 am-10:41 am

1 stop23h 15m

$570

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 4/14

7:02 pm-10:30 am

2 stops16h 28m

Panama City Tocumen Intl

Wed 4/22

11:25 am-8:58 am

3 stops20h 33m

$576

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 5/8

7:55 pm-10:30 am

2 stops15h 35m

Panama City Tocumen Intl

Fri 5/15

3:50 pm-9:27 pm

2 stops28h 37m

$577

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 4/14

7:02 pm-10:30 am

2 stops16h 28m

Panama City Tocumen Intl

Wed 4/22

5:30 am-8:58 am

2 stops26h 28m

$580

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 5/8

7:55 pm-2:55 pm

3 stops20h 00m

Panama City Tocumen Intl

Fri 5/15

3:50 pm-9:27 pm

2 stops28h 37m

$583

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 4/15

7:02 pm-2:55 pm

3 stops20h 53m

Panama City Tocumen Intl

Wed 4/22

5:30 am-8:58 am

2 stops26h 28m

$586

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 5/9

7:55 pm-10:30 am

2 stops15h 35m

Panama City Tocumen Intl

Sat 5/16

3:50 pm-9:31 am

2 stops16h 41m

$588

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sun 4/26

7:00 am-10:30 am

2 stops28h 30m

Panama City Tocumen Intl

Sat 5/2

3:50 pm-2:58 pm

2 stops22h 08m

$618

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 4/15

7:02 pm-2:55 pm

3 stops20h 53m

Panama City Tocumen Intl

Wed 4/22

11:25 am-8:58 am

3 stops20h 33m

$621
Quickest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 4/14

6:55 pm-4:04 am

1 stop10h 09m

Panama City Tocumen Intl

Wed 4/22

10:55 pm-9:47 am

1 stop9h 52m

$629

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Buffalo to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Buffalo to Panama City Tocumen Intl?

United Airlines and American Airlines are the most popular carriers operating from Buffalo to Panama City Tocumen Intl

When to book flights from Buffalo to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Panama City (BUF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama City

Fastest flight time

8h 53m

Direct flights

None
The fastest flight from Buffalo to Panama City takes 8h 53m
There are no direct flights from Buffalo to Panama City. There are no popular flight routes from Buffalo to Panama City.
Search flight deals

  • How far is Buffalo to Panama City Tocumen Intl by plane?

    Buffalo and Panama City Tocumen Intl are 2341.1 mi apart from one another. Flights usually cover this in 8h 53m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Buffalo Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Panama City?

Best airlines flying from Buffalo to Panama City

Compare and see reviews for airlines that fly from Buffalo to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $461Free CancellationRating
7.9
8,356 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama City?

Finding the right flight to Panama City from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Buffalo to Panama City with flexible booking policies on momondo?

Flights from Buffalo to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Buffalo.

I’m not ready to book a flight from Buffalo to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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