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Cheap flights from Buffalo to Panama City from $570

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama City departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Buffalo to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:35 pm - 10:30 am
BUF
-
PTY
18h 55m
2 stops
Multiple Airlines Logo
3:50 pm - 8:24 am
PTY
-
BUF
15h 34m
2 stops
$570Multiple Airlines
Thu, Oct 15 - Mon, Oct 19
Multiple Airlines Logo
8:00 pm - 2:55 pm
BUF
-
PTY
18h 55m
3 stops
Multiple Airlines Logo
3:50 pm - 8:27 am
PTY
-
BUF
16h 37m
2 stops
$614Multiple Airlines
Fri, Nov 6 - Mon, Nov 9
Multiple Airlines Logo
3:50 pm - 10:30 am
BUF
-
PTY
19h 40m
2 stops
Multiple Airlines Logo
3:50 pm - 2:55 pm
PTY
-
BUF
22h 05m
2 stops
$670Multiple Airlines
Sat, Jun 20 - Sat, Jul 4
United Airlines Logo
6:30 am - 7:31 pm
BUF
-
PTY
14h 01m
1 stop
United Airlines Logo
9:45 am - 11:11 pm
PTY
-
BUF
12h 26m
1 stop
$698United Airlines
Thu, Oct 15 - Mon, Oct 19
United Airlines Logo
6:30 am - 7:31 pm
BUF
-
PTY
14h 01m
1 stop
United Airlines Logo
3:30 pm - 1:11 pm
PTY
-
BUF
20h 41m
2 stops
$702United Airlines
Thu, Oct 15 - Mon, Oct 19
United Airlines Logo
10:34 am - 4:04 am
BUF
-
PTY
18h 30m
1 stop
United Airlines Logo
10:55 pm - 6:05 pm
PTY
-
BUF
18h 10m
1 stop
$703United Airlines
Mon, Jul 20 - Mon, Jul 27
Multiple Airlines Logo
10:25 am - 1:55 am
BUF
-
PTY
16h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 8:24 am
PTY
-
BUF
15h 34m
2 stops
$705Multiple Airlines
Mon, Aug 24 - Wed, Sep 23
United Airlines Logo
5:58 pm - 2:14 pm
BUF
-
PTY
21h 16m
2 stops
United Airlines Logo
3:30 pm - 9:28 am
PTY
-
BUF
16h 58m
2 stops
$707United Airlines
Mon, Aug 17 - Sat, Aug 22
Multiple Airlines Logo
6:00 am - 1:55 am
BUF
-
PTY
20h 55m
2 stops
Multiple Airlines Logo
11:25 am - 8:24 am
PTY
-
BUF
19h 59m
3 stops
$711Multiple Airlines
Mon, Aug 24 - Wed, Sep 23
United Airlines Logo
6:00 am - 4:04 am
BUF
-
PTY
23h 04m
1 stop
United Airlines Logo
3:30 pm - 9:28 am
PTY
-
BUF
16h 58m
2 stops
$715United Airlines
Mon, Aug 17 - Sat, Aug 22

American Airlines flights from Buffalo to Panama City

Our best American Airlines deals on Buffalo to Panama City flight tickets
American Airlines
Jun 28
BUF7:32 pmBuffalo
17h 41m
2 stops
PTY12:13 pmPanama City Tocumen Intl
Jul 2
PTY1:14 pmPanama City Tocumen Intl
19h 23m
2 stops
BUF9:37 amBuffalo
$805
American Airlines
Aug 4
BUF5:25 pmBuffalo
20h 14m
2 stops
PTY12:39 pmPanama City Tocumen Intl
Aug 18
PTY1:39 pmPanama City Tocumen Intl
19h 00m
2 stops
BUF9:39 amBuffalo
$1,057
American Airlines
Aug 4
BUF7:35 pmBuffalo
18h 04m
2 stops
PTY12:39 pmPanama City Tocumen Intl
Aug 18
PTY1:39 pmPanama City Tocumen Intl
19h 00m
2 stops
BUF9:39 amBuffalo
$1,077

United Airlines flights from Buffalo to Panama City

Our best United Airlines deals on Buffalo to Panama City flight tickets
United Airlines
Oct 15
BUF6:30 amBuffalo
14h 01m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Oct 19
PTY9:45 amPanama City Tocumen Intl
12h 26m
1 stop
BUF11:11 pmBuffalo
$698
United Airlines
Oct 15
BUF6:30 amBuffalo
14h 01m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Oct 19
PTY3:30 pmPanama City Tocumen Intl
20h 41m
2 stops
BUF1:11 pmBuffalo
$702
United Airlines
Jul 20
BUF10:34 amBuffalo
18h 30m
1 stop
PTY4:04 amPanama City Tocumen Intl
Jul 27
PTY10:55 pmPanama City Tocumen Intl
18h 10m
1 stop
BUF6:05 pmBuffalo
$703

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 10/15

4:35 pm-10:30 am

2 stops18h 55m

Panama City Tocumen Intl

Mon 10/19

3:50 pm-8:24 am

2 stops15h 34m

$570

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 11/6

8:00 pm-2:55 pm

3 stops18h 55m

Panama City Tocumen Intl

Mon 11/9

3:50 pm-8:27 am

2 stops16h 37m

$614

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 6/20

3:50 pm-10:30 am

2 stops19h 40m

Panama City Tocumen Intl

Sat 7/4

3:50 pm-2:55 pm

2 stops22h 05m

$670
Quickest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 10/15

6:30 am-7:31 pm

1 stop14h 01m

Panama City Tocumen Intl

Mon 10/19

9:45 am-11:11 pm

1 stop12h 26m

$698

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 10/15

6:30 am-7:31 pm

1 stop14h 01m

Panama City Tocumen Intl

Mon 10/19

3:30 pm-1:11 pm

2 stops20h 41m

$702

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 7/20

10:34 am-4:04 am

1 stop18h 30m

Panama City Tocumen Intl

Mon 7/27

10:55 pm-6:05 pm

1 stop18h 10m

$703

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/24

10:25 am-1:55 am

2 stops16h 30m

Panama City Tocumen Intl

Wed 9/23

3:50 pm-8:24 am

2 stops15h 34m

$705

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/17

5:58 pm-2:14 pm

2 stops21h 16m

Panama City Tocumen Intl

Sat 8/22

3:30 pm-9:28 am

2 stops16h 58m

$707

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/24

6:00 am-1:55 am

2 stops20h 55m

Panama City Tocumen Intl

Wed 9/23

11:25 am-8:24 am

3 stops19h 59m

$711

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/17

6:00 am-4:04 am

1 stop23h 04m

Panama City Tocumen Intl

Sat 8/22

3:30 pm-9:28 am

2 stops16h 58m

$715

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Buffalo to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Panama City (BUF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama City

Fastest flight time

12h 42m

Direct flights

None
The fastest flight from Buffalo to Panama City takes 12h 42m
There are no direct flights from Buffalo to Panama City. There are no popular flight routes from Buffalo to Panama City.
Search flight deals

Frequently asked questions about flying from Buffalo to Panama City

  • How far is Buffalo to Panama City Tocumen Intl by plane?

    Buffalo and Panama City Tocumen Intl are 2341.1 mi apart from one another. Flights usually cover this in 12h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Buffalo Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Panama City?

Best airlines flying from Buffalo to Panama City

Compare and see reviews for airlines that fly from Buffalo to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $517Free CancellationRating
7.9
8,396 reviews
Search Delta flights

Frequently asked questions about flying from Buffalo to Panama City

  • How do I get Price Alerts for flights from Buffalo to Panama City?

    You can take advantage of momondo’s Price Alerts by first searching for your flights to Buffalo from Panama City. Flight offers will be shown to you in real-time. From there you can create a Price Alert by using our on-site widget.

  • How can I save money on flights from Buffalo to Panama City with momondo?

    Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore”. Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama City?

Finding the right flight to Panama City from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Buffalo to Panama City with flexible booking policies on momondo?

Flights from Buffalo to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Buffalo.

I’m not ready to book a flight from Buffalo to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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