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Cheap flights from Buffalo to Panama City from $261

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama City departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:45 pm - 10:30 am-
14h 45m
Multiple Airlines Logo
3:50 pm - 9:04 am-
17h 14m
$553Multiple Airlines
Fri, Jan 29 - Mon, Mar 1
Multiple Airlines Logo
7:45 pm - 10:30 am-
14h 45m
Multiple Airlines Logo
7:50 pm - 9:05 am-
13h 15m
$553Multiple Airlines
Sun, Jan 17 - Thu, Jan 28
Multiple Airlines Logo
8:00 pm - 10:30 am-
15h 30m
Multiple Airlines Logo
3:50 pm - 4:19 pm-
23h 29m
$553Multiple Airlines
Sat, Oct 24 - Wed, Oct 28
Multiple Airlines Logo
8:00 pm - 10:30 am-
15h 30m
Multiple Airlines Logo
11:25 am - 8:27 am-
20h 02m
$559Multiple Airlines
Sat, Oct 24 - Wed, Oct 28
Multiple Airlines Logo
7:45 pm - 2:55 pm-
19h 10m
Multiple Airlines Logo
7:50 pm - 1:39 pm-
17h 49m
$559Multiple Airlines
Fri, Jan 29 - Mon, Mar 1
Multiple Airlines Logo
7:45 pm - 2:55 pm-
19h 10m
Multiple Airlines Logo
7:50 pm - 9:05 am-
13h 15m
$559Multiple Airlines
Sun, Jan 17 - Thu, Jan 28
Multiple Airlines Logo
7:45 pm - 2:55 pm-
19h 10m
Multiple Airlines Logo
11:25 am - 9:05 am-
21h 40m
$564Multiple Airlines
Wed, Jan 20 - Wed, Feb 3
Delta Logo
6:00 am - 1:55 pm-
7h 55m
Delta Logo
3:20 pm - 11:55 pm-
8h 35m
$693Delta
Tue, Jan 5 - Wed, Jan 13
Delta Logo
6:00 am - 1:55 pm-
7h 55m
Delta Logo
3:20 pm - 11:55 pm-
8h 35m
$693Delta
Wed, Jan 20 - Wed, Feb 3
Delta Logo
6:00 am - 1:55 pm-
7h 55m
Delta Logo
3:20 pm - 11:55 pm-
8h 35m
$693Delta
Tue, Jan 5 - Thu, Jan 14

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Delta flights from Buffalo to Panama City

Our best Delta deals on Buffalo to Panama City flight tickets
Delta
Jan 20
BUF6:00 amBuffalo
7h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Feb 3
PTY3:20 pmPanama City Tocumen Intl
8h 35m
1 stop
BUF11:55 pmBuffalo
$693
Delta
Jan 6
BUF6:59 pmBuffalo
18h 56m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 13
PTY3:20 pmPanama City Tocumen Intl
8h 35m
1 stop
BUF11:55 pmBuffalo
$704
Delta
Jan 6
BUF6:59 pmBuffalo
18h 56m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 16
PTY1:40 pmPanama City Tocumen Intl
10h 15m
1 stop
BUF11:55 pmBuffalo
$734

United Airlines flights from Buffalo to Panama City

Our best United Airlines deals on Buffalo to Panama City flight tickets
United Airlines
Jan 20
BUF6:45 pmBuffalo
22h 27m
2 stops
PTY5:12 pmPanama City Tocumen Intl
Feb 3
PTY8:55 amPanama City Tocumen Intl
13h 42m
2 stops
BUF10:37 pmBuffalo
$697
United Airlines
Jan 4
BUF7:00 amBuffalo
22h 10m
2 stops
PTY5:10 amPanama City Tocumen Intl
Jan 11
PTY4:41 pmPanama City Tocumen Intl
20h 29m
2 stops
BUF1:10 pmBuffalo
$714
United Airlines
Jan 5
BUF7:00 amBuffalo
13h 02m
2 stops
PTY8:02 pmPanama City Tocumen Intl
Jan 11
PTY4:41 pmPanama City Tocumen Intl
24h 06m
2 stops
BUF4:47 pmBuffalo
$717

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 1/29

7:45 pm-10:30 am

2 stops14h 45m

Panama City Tocumen Intl

Mon 3/1

3:50 pm-9:04 am

2 stops17h 14m

$553

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sun 1/17

7:45 pm-10:30 am

2 stops14h 45m

Panama City Tocumen Intl

Thu 1/28

7:50 pm-9:05 am

2 stops13h 15m

$553

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 10/24

8:00 pm-10:30 am

2 stops15h 30m

Panama City Tocumen Intl

Wed 10/28

3:50 pm-4:19 pm

2 stops23h 29m

$553

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 10/24

8:00 pm-10:30 am

2 stops15h 30m

Panama City Tocumen Intl

Wed 10/28

11:25 am-8:27 am

3 stops20h 02m

$559

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 1/29

7:45 pm-2:55 pm

3 stops19h 10m

Panama City Tocumen Intl

Mon 3/1

7:50 pm-1:39 pm

2 stops17h 49m

$559

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sun 1/17

7:45 pm-2:55 pm

3 stops19h 10m

Panama City Tocumen Intl

Thu 1/28

7:50 pm-9:05 am

2 stops13h 15m

$559

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 1/20

7:45 pm-2:55 pm

3 stops19h 10m

Panama City Tocumen Intl

Wed 2/3

11:25 am-9:05 am

3 stops21h 40m

$564
Quickest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 1/5

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 1/13

3:20 pm-11:55 pm

1 stop8h 35m

$693

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 1/20

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 2/3

3:20 pm-11:55 pm

1 stop8h 35m

$693

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 1/5

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 1/14

3:20 pm-11:55 pm

1 stop8h 35m

$693

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Buffalo to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Buffalo to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you’re not able to fly to Panama City in August, then March is your next best option. Flight prices from Buffalo to Panama City during March average around $0.

When to book flights from Buffalo to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Panama City (BUF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama City

Fastest flight time

13h 45m

Direct flights

None
The fastest flight from Buffalo to Panama City takes 13h 45m
There are no direct flights from Buffalo to Panama City. There are no popular flight routes from Buffalo to Panama City.
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Frequently asked questions about flying from Buffalo to Panama City

  • How far is Buffalo to Panama City Tocumen Intl by plane?

    Buffalo and Panama City Tocumen Intl are 2341.1 mi apart from one another. Flights usually cover this in 13h 45m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Buffalo Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Buffalo Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Panama City?

Best airlines flying from Buffalo to Panama City

Compare and see reviews for airlines that fly from Buffalo to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $517Free CancellationRating
7.8
8,482 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Panama City?

Finding the right flight to Panama City from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Buffalo to Panama City with flexible booking policies on momondo?

Flights from Buffalo to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Buffalo.

I’m not ready to book a flight from Buffalo to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Buffalo. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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